BIS和CSI在老年患者异丙酚靶控镇静中的应用被引量：3

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摘要目的比较在无手术刺激状态下,老年患者靶控输注异丙酚不同镇静程度时,大脑状态指数(CSI)与脑电双频指数(BIS)监测的临床应用价值。方法老年择期手术患者18例,年龄65～78岁,ASAⅠ～Ⅱ级,所行手术不限。全麻诱导前行异丙酚靶控输注(TCI)镇静,靶浓度由0.5μg/ml开始,递增梯度为0.5μg/ml,间隔时间为5min,直至镇静评分(OAA/S)为0后5min停止。试验中,监测并记录患者的CSI、BIS值,间隔20s行OAA/S镇静评分。记录靶控输注系统预测的效应部位浓度值(CE),每变化0.1μg/ml时的数值及时间。结果镇静程度(OAA/S)的变化与CE、BIS、CSI有线性回归关系:与CE呈负相关,与BIS、CSI呈正相关。相关性的程度依次为CE>BIS>CSI。BIS与CSI的监测均能很好地反映患者的镇静程度,但两者对OAA/S变化的相关性无统计学差异。结论随着CE的变化,BIS和CSI可以很好地反映异丙酚对老年患者的镇静程度,CSI的灵敏度更高一些;但是两者对预测体动反应较差。

作者陈莉丽熊云川熊平李达

机构地区江西省南昌市第三医院麻醉科中南大学湘雅医学院第一附属医院麻醉科

出处《江西医药》 CAS 2007年第10期920-922,共3页 Jiangxi Medical Journal

关键词双异丙酚靶控输注 CSI BIS

分类号 R971.2 [医药卫生—药品]

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