摘要
目的了解环境因素与先天性心脏病的关系,找出其危险因素,为今后预防先心病探讨有效的预防模式。方法调查100例先天性心脏病患者与200例对照,按照1:2配比进行病例对照研究(按照性别、年龄、居住地进行匹配,病例通过临床及彩超进行诊断)。设计《幼儿出生质量影响因素调查表》,对先心病儿童及对照儿童父母用采访的方式进行调查,对暴露因素进行条件Logistic回归分析,比较两组调查结果,以获取他们是否暴露于相关环境危险因素的资料。结果膳食营养、感染、复性生活事件、烟酒、是否接触农药与CHD的发生有一定的联系。结论环境因素与先心病的发生有一定的关系。
Obejctive：To assess the environment risk factors of CHD and to discuss the effective methods to prevent CHD. Methods： A paired case- control study （case=100 control = 200） was used. Cases and controls were paired according to age, sex and living area. Cases were correctly diagnosed by clinical and coloredultrasonic. The investigate questionnaire of new born baby was designed, and the parents of casese and controls by visitation were investigated to obtain the material about whether they had contacted the relevant risk factors before and during pregnant. Then the environmental fac- tors were studied and analyzed by simple and mtthi conditional logistic regression. Results： Nutrition, infection, minute life events, alcoholic drinks and tobacco, exposure to pesticides had relations to CHD. Conclusion： There are some correlations between environmental factors and CHD.
出处
《泰山医学院学报》
CAS
2007年第5期338-340,共3页
Journal of Taishan Medical College
关键词
先天性心脏病
环境因素
病例对照研究
congenital heart disease
environmental factors
case-control study
