摘要
妊娠相关乳腺癌（PABC）预后很差，肿瘤易于发生转移，所以越来越多地受到了人们的重视，PABC发生机制的研究主要集中在妊娠相关激素的作用和妊娠哺乳后乳腺的复旧上，妇女妊娠期间雌二醇、孕激素和人绒毛膜促性腺激素等激素水平升高与乳腺癌的发生发展关系密切，在妊娠哺乳期间乳腺组织的变化提供了有利于肿瘤发生和转移的微环境。
Pregnancy-associated breast cancer （PABC） has a poor prognosis, and is easy to invade and metastasize. It receives more and more attension. Studies about the mechanisms of PABC genesis focus on the action of pregnancy-related hormones and mammary gland reconverting after breast-feeding. The change of hormone level of estradiol, progestogen and β-HCG and the mammary gland microenvironment may affect the proliferation and cancerization of glandular epithelium, and induce the carcinogenesis, progression and metastasis of breast cancer.
出处
《国际肿瘤学杂志》
CAS
2007年第11期835-838,共4页
Journal of International Oncology
基金
天津市科技发展计划项目（043115211-1）
关键词
乳腺肿瘤
激素类
Breast neoplasms
Hormones
