摘要
目的观察静脉滴注地尔硫对不稳定型心绞痛合并顽固性高血压患者的治疗效果和安全性。方法30例不稳定型心绞痛合并顽固性高血压且扩血管药物疗效不好的患者,静脉滴注地尔硫20￣50mg后48h内,观察心绞痛症状、血压、心率变化、心电图转变及副作用。结果静脉滴注地尔硫治疗心绞痛总有效率为96.67%。30例中有29例用药48h内心绞痛次数减少(3.3±2.0)次,发作持续时间缩短(11±5)min,静脉滴注地尔硫后血压、心率明显降低,收缩压由(23±4)kPa降为(18±3)kPa(P<0.01);舒张压由(12.9±1.7)kPa降为(10.2±2.2)kPa(P<0.01)。11例患者用药后ST段恢复正常或明显改善,副作用少。结论静脉滴注地尔硫对不稳定型心绞痛合并顽固性高血压的治疗有效、安全。
Objective To study the efficacy and safety of dihiazem by intravenous dripping on trustable angina patients （UAP） accompanied obstinate hypertension. Methods Thirty cases of UAP with obstinate hypertension controlled unsatisfactory by other vessl expansionary medicines were treated with 20-50 mg dihiazem by ivgtt within 48 hours .The symptom of ischemic,the change of blood pressure, heart rate and EKG as well as adverse reactions were observed for 48 hours.Results The total effective rate was 96.67%. The number of ischemie in 29 patients significantly reduced （3.3 ± 2.0）and the duration of isehemic episodes shortened （11 ± 5min）. Blood pressure and heart rate cut down .The contractive pressure degraded from （23 ± 4）to 08 ± 3） kPa （P〈0.01）and the diastolic blood pressure reduced from （12.9 ± 1.7）kPa to （10.2 ± 2.2）kPa] （P〈0：01）. ST-segment retuned to nomal or improved in ll patients. Few side effect was found. Conclusions Dihiazem intravenous dripping is effective and safe for UAP combined with obstinately hypertension.
出处
《基层医学论坛（B版）》
2007年第12期1059-1060,共2页
Public Medical Forum Magazine
