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调脂治疗对增强肥胖2型糖尿病患者胰岛素敏感性的疗效观察 被引量:2

Lipid-adjusting Therapy can Enforce Insulin Sensitivity of Type 2 Diabetes Mellitus Patients with Obesity
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摘要 目的:提高糖尿病患者的达标率,减少胰岛素用量。方法:测定普伐他汀治疗前后病人的空腹血糖、餐后2h血糖、糖化血红蛋白、空腹胰岛素水平,计算胰岛素敏感指标(ISI)。结果:调脂治疗组6周后ISI上升较对照组差异有显著性(P<0.05),空腹血糖及餐后血糖治疗组与对照组均有下降,但无统计学意义。治疗组空腹胰岛素和C肽治疗后较前明显下降,差异有显著性(P<0.05)。结论:经调脂治疗后病人ISI增加有显著性,血糖达标后胰岛素用量明显减少。 Objective :To increase the rate of glucose control and to reduce Serum fasting glucose, post load glucose , glycosylated hemoglobin and fasting the dose of insulin. Method: insulin were measured before pravastatin therapy and Meter therapy respectively, and calculated the insulin sensitivity index ( ISI ). Result: After lipid -adjusting therapy for six weeks, there was a significant increase in ISI intherapy groop compared to control groop. Serum fasting cance. Serum fasting insulin an glucose and post load glucose in both groop all decreased, and had no signifi- d C peptide were decreased after treatment , there was a significance between two groops. Conclusion :There were significant insulin sensitivity index in lipid - adjusting group than in con- trois. The dose of insulin was reduced obviously after good glucose control.
作者 李莉
出处 《河北医学》 CAS 2007年第2期143-144,共2页 Hebei Medicine
关键词 糖尿病 2型 肥胖 胰岛素 敏感性 Diabetes Type 2 Obesity Insulin Sensitivity
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