摘要
目的:评价海捷亚对轻、中度原发性高血压患者降压作用的稳定性。方法:选取2006年1月至2006年10月我院门诊或住院患者中轻、中度原发性高血压患者40例,每日口服海捷亚1片,平均疗程8周(包括安慰剂洗脱期2周),于服药前及服药8周后进行动态血压监测并计算谷峰比值与平滑指数。结果:治疗8周后:①与服药前比较平均收缩压和平均舒张压分别下降17.9mmHg和12.7mmHg,脉压差明显减少,差异具有显著性(P<0.05);②用药后收缩压、舒张压谷峰比值分别为76.7%和71.2%;③平滑指数为SBP1.14±0.39,DBP 1.09±0.27。结论:海捷亚对轻、中度原发性高血压具有平稳的降压作用。
Objective： To evaluate the smooth control effect of Hyzaar in patients who sufferred from mild- moderate essential hypertention. Method： 40 patients out of outpatients or inpatients with mild - moderate essential hypertention from Jan. 2006 to Oct. 2006 were included in this study. All cases were giv- en Hyzaar 1 table once a day for 8 weeks I including placebo elution for 2 weeks }. A 24 - hour ambulatory blood pressure monitoring was performed, respectively at pre - treatment and after 8 - week treatment. More- over, T/P ratio and smoothness index were tested. Result： After 8 -week administration, firstly, the mean systolic and diastolic blood pressure decreased 17.9 and 12.7mmHg respectively. The pulse pressure also dropped significantly. Secondly, the T/P ratio of systolic blood pressure was 76.7%, the diastolic blood pressure was 71.2%. Thirdly, the smoothness index of systolic blood pressure was 1.14 ＋ 0.39, the dias- tolic blood pressure was 1.09 ＋ 0.27. Conclusion： Hyzaar has smoothly control effect on the patients with mild- moderate essential hypertention.
出处
《河北医学》
CAS
2007年第2期127-130,共4页
Hebei Medicine
