摘要
47例经病理检查确诊的恶性肿瘤，包括肺癌、乳腺癌、淋巴瘤、卵巢癌分别应用同样方案和剂量的联合化疗，并采用交叉自身配对对照的方法，对这些化疗病例同时加用或不加用吉粒芬作对照研究，比较两组病人中性粒细胞绝对数（ANC）的动态变化。结果证明，吉粒芬可减轻化疗后ANC降低的程度，缩短粒细胞缺乏症的持续时间，促进ANC的恢复，无明显毒副反应，可作为肿瘤化疗中有价值的辅助药物。
Forty-Seven cases of malignancy including lung cancer, malignant lymphoma, breast cancer and o-varian cancer were treated with combined chemotherapy of the same scheme and dose. Each patient re ceived one treatment cycle (with Jilifen)and one control cycle(without Jilifen). The chenges of absoluteneutrophil count during the chemotherapy course between a treatment cycle and a control cycle were com pared. The results showed that in the cycle treated with Jilifen neutropenia could be prevented or attenuated, with the neutrophil nadir higher and neutrophil recovery earlier as compared to the control cycles. Noobvious side effect was found. The study confirmed the value of Jilifen as a valuable adjuvant in cancerchemotherapy.
出处
《河南肿瘤学杂志》
1997年第4期259-261,共3页
Henan Journal of Oncology
关键词
吉粒芬
肿瘤
药物疗法
rhGCSF
Jilifen
granulocyte colony-stimulating Factor(G-CSF)
tumor
chemotherapy
