摘要
目的:观察小儿无血预充体外循环术后机体的临床和实验室检查变化。方法:选择体重10～20kg 常见先心病40例,全部采用无血预充,观察术后血球压积、血红蛋白、血小板、血浆蛋白和血气分析等变化,并与同期40例有血预充对照。结果:两组病例术后血球压积、血红蛋白和血气分析相比无显著差异(P>0.05)。无血预充组术后早期血小板和血浆蛋白明显下降,但术后7天内逐渐恢复到术前水平。24小时和总的纵隔引流量分别减少26.7%和22.2%,70%患儿术后无需输血,表明无血预充体外循环具有减少术后并发症和节约用血的作用。
Objective:To observe the clinical and laboratorial responses to non-blood prime (NBP)during cardiopulmonary bypass(CPB)in children.Methods:A total NBP was used during open heart operations for 40 children(bodyweight 10～20kg)with common congenital heart de- fects.Their hematocrit,hemoglobin,platelet,plasm protein and blood gas were analyzed.The results were compared with the other 40 patients using blood prime.Results:The mean hema- tocrit,hemoglobin and blood gas analysis were similar in both groups after CPB(P<0.05).In NBP group,platelet and hemoglobin protein decreased immediately after the operation,but in- creased gradually and reached the preoperative level after 7 postoperative days.Twenty-four hours and total postoperative mediastinal drainage decreased by 26.7% and 22.2% respectively.Blood transfusion after operation was not necessary for 70% of the patients.Conclusion:NBP may re- duce postoperative complications and blood transfusions.
出处
《中华小儿外科杂志》
CSCD
1997年第4期210-212,共3页
Chinese Journal of Pediatric Surgery
关键词
心脏缺损
先天性
血液稀释
体外循环
儿童
Heart defects,congenital
Hemodilution
Extracorporal circulation
