摘要
目的通过临床分析对照了解盐酸戊乙奎醚治疗有机磷中毒的作用和优缺点。方法随机将有机磷农药中毒患者分为对照组和治疗组,每组各60例。治疗组应用氯磷定和盐酸戊乙奎醚;对照组应用氯磷定和常规阿托品救治。结果中毒症状消失时间和ChE活力恢复时间治疗组明显短于对照组。不良反应治疗组明显少于对照组。结论盐酸戊乙奎醚是一种新型长效抗胆碱药物,在治疗有机磷中毒方面具有阿托品所没有的高选择性、低毒性、安全、有效的作用。
Objective To evaluate the effect advantage and disadvantage of penehyclidime hydrochloride in treatment of organic phosphorus poisoning. Methods One hundred and twenty cases of organophosphorus poisoning by digestive tract way were randomly divided into control group （n = 60）and treatment group （n = 60）. The treatment group were treated by pyraloximi methochloridum and penehyclime hydrochloride. The control group were treated by pyraloximi methochloridum and atropine. Results Between the two groups, the treatment group uses less time in the disappear- ance of poisoning symptom than the control group ; the treatment group has a shorter ChE recovery time and slighter side effect than the control group. Conclusions It is suggested by the result that penehyclidime hydrochloride is an anticholines ageat in treatment of organic phosphorus poisoning. And it has the highly selective, low toxicity, safe, highly effective effect which atropine doesn＇ t have.
出处
《医学信息（手术学分册）》
2007年第8期694-695,697,共3页
Medical Information Operations Sciences Fascicule
关键词
盐酸戊乙奎醚
阿托品
有机磷中毒
penehyclime hydrochloride
atropine
organphorsphorus poisoning
