摘要
目的探讨食管癌根治术后放射治疗的价值。方法2003年7月至2007年1月对186例食管癌进行根治术后预防性放射治疗并与单纯手术治疗分组比较。结果术后放射治疗组1、3年生存率为78.6%、54.5%,单纯手术组1、3年生存率为73.5%、36.2%,差异有统计学意义(P<0.01)。有淋巴结转移患者的3年生存率(29.9%)低于无淋巴结转移患者的3年生存率(42.5%),差异无统计学意义(P>0.05)。无淋巴结转移者术后放射治疗组3年生存率较单纯手术组明显提高,差异有统计学意义(P<0.05)。结论食管癌根治术后辅助放射治疗可提高局部控制率和生存率,无淋巴结转移者术后行放射治疗亦是必要的。
Objective To investigate the value of prophylactic postoperative radiotherapy for esophageal carcinoma. Methods From July 2003 to January 2007, 186 esophageal carcinoma patients were divided into the prophylactic postoperative radiotherapy group and the surgery alone group. Results The 1-,3-year survival rate of prophylactic postoperative radiotherapy group was 78.6% and 54.5%. The 1-,3-year survival rate of surgery alone group was 73.5% and 36.2%. There was significant difference（ P 〈 0.01 ）. The 3-year survival rate between positive lymph nodes and negative lymph nodes was no significant difference. But, the 3-year survival rate of prophylactic postoperative radiotherapy group was higher than that of surgery alone group for negative lymph nodes. Conclusions The local control and survival rate can be improved for patients with prophylactic postoperative radiotherapy for esophageal carcinoma. It is necessary to perform prophylactic postoperative radiotherapy for negative lymph nodes.
出处
《肿瘤基础与临床》
2007年第6期520-521,共2页
journal of basic and clinical oncology
关键词
食管癌
根治术后
放射治疗
esophageal neoplasms
postoperative
radiotherapy
