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部分脾动脉栓塞联合肝动脉栓塞治疗原发性肝癌并脾亢的临床研究 被引量:3

Study on Primary Hepatocellular Carcinoma Associated with Hypersplenism Treated by Partial Splenic Embolization Combined with Hepatic Arterial Embolization
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摘要 【目的】探讨部分脾动脉栓塞联合肝动脉栓塞治疗原发性肝癌合并脾功能亢进的意义。【方法】62例原发性肝癌患者,随机分为两组:每组31例,A组为实验组,采用部分脾动脉栓塞联合肝动脉栓塞的方法治疗;B组为对照组,单用肝动脉栓塞的方法治疗。【结果】A组与B组比较患者外周血象明显改善,部分脾动脉栓塞术后3天1、周、2周外周血白细胞、血小板较栓塞前明显提高,A组出现食管胃底静脉曲张破裂出血及腹水的患者明显少于B组(P<0.01)。两组均未见严重并发症出现。【结论】部分脾动脉栓塞联合肝动脉栓塞治疗合并脾亢的原发性肝癌是安全、有效的,可提高外周血小板、白细胞,降低食管胃底静脉曲张破裂出血及腹水发生率。 [Objective]To investigate the value of partial splenic embolization(PSE) combined with transcatheter hepatic arterial embolization(TAE) for the treatment of primary hepatocellular carcinoma (PHC) with portal hypertension and hypersplenism. [Methods]Efficacy of 31 patients with PSE combined with TAE and 31 patients with single TAE yeas observed. [Results]Satisfactory effects were achieved in PSE combined with TAE group in terms of correction of blood cell counts, ascites, esophageal and gastric varicose bleeding compared with cases treated with TAE alone. No severe complication occurred in all cases. [Conclusion]PSE combined with TAE is safe and effective for the treatment of patients with PHC associated with liver cirrhosis, portal hypertension and hypersplenism. It can improve peripheral platelet, WBC, and reduce the rate of ascites and esophageal and gastric varicose bleeding.
出处 《医学临床研究》 CAS 2007年第11期1941-1943,共3页 Journal of Clinical Research
关键词 肝肿瘤/并发症 脾功能亢进/治疗 栓塞 治疗性 脾动脉 肝动脉 liver neoplasms/CO hypersplenism/TH embolization, therapeutic splenic artery hepatic artery
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