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小剂量瑞芬太尼辅助下腹部手术硬膜外麻醉的临床观察 被引量:3

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摘要 目的比较下腹部手术在硬膜外麻醉时辅助应用瑞芬太尼的临床作用。方法60例需行下腹部手术病人随机分成两组。A组为瑞芬太尼组(n=30),B组为对照组(n=30),两组患者均选择L1~2行推管穿刺向头端插管硬膜外麻醉,局麻药均选用2%利多卡因,A组患者在麻醉效果确切后手术开始切皮前静注瑞芬太尼0.25ug/kg,继之用微量泵(浙江产wzx-50F2)持续输注瑞芬太尼0.05~0.1ug/kg.min,术毕缝合皮肤时停用瑞芬太尼。B组患者未用任何辅助药。观察两组患者手术中血流动力学变化,镇痛效果及镇静情况。结果两组患者在硬膜外麻醉效果满意后,手术开始后在进入腹腔前(T2),两组患者的心率、血压、较麻醉前(T1)均有所下降,与麻醉前相比差异有显著性。手术进入腹腔操作后(T3),A组心率,血压与进腹腔前(T2)相比波动较小,两者变化相比差异无显著性(P>0.05)。而B组心率、血压与进腹腔前相比波动较大。两者变化相比差异有显著性(P<0.01)。两组的口述描绘四级评分(VDS)比较差异也有显著性(P<0.01)而两组之间的镇静深度评分(OAA/S)比较有一些区别,但两组之间比较差异无显著性(P>0.05)。结论小剂量瑞芬太尼作为下腹部手术硬膜外麻醉的辅助用药,具有镇痛效果良好,能消除手术操作中的牵拉反应,能保持术中血流动力学的稳定,且能保持术中的清醒。
作者 欧阳帆 彭丽
出处 《海南医学》 CAS 2007年第12期93-94,共2页 Hainan Medical Journal
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