摘要
目的:探讨经深低温冷冻处理(-80℃)、未经处理同种异体肌腱和自体肌腱移植后的生物力学性能改变。方法:采用兔跟腱缺损修复模型,分为深低温冷冻处理同种异体肌腱移植组(深低温异体组)、未经处理同种异体肌腱移植组(未处理异体组)和自体肌腱移植组(自体组)。分别在移植前及移植后第3、6周时对三组跟腱进行生物力学性能测试。结果:深低温异体组移植后第3、第6周时其生物力学性能测试的各项指标均优于未处理异体组(P<0.05),而与自体组无统计学意义(P>0.05)。结论:深低温冷冻处理同种异体肌腱移植在生物力学方面的表现与自体肌腱移植结果基本相同,可替代自体肌腱应用于移植修复肌腱缺损。
Objective： To discuss the change of deep frozen treated （-80℃）,untreated allogeneic and autologous tendon transplantation biomeehanical properties.Methods： Rabbit models of achilles tendon defect were used, and three groups were set up, cryopreservation deep hypothermia frozen allograft tendon transplantation （deep hypothermia allograft group）, untreated allograft tendon transplantation（untreated autologous group） and autologous tendon transplant （autologous group）. Three groups were conducted achilles biomechanical testing before and after transplantation in the third and sixth weeks. Results：Deep hypothermia allograft group＇s every indicators were better than untreated autologous group＇s before and af ter transplantation in the third and sixth weeks（P〈0.05）, no significant difference compared with autologous group （P＇M）.05）. Conclusion： Deep hypothermia frozen allograft tendon transplantation and autologous tendon transplantation＇s results in performance of biomeehanics are basically the same, and can replace autologous tendon in tendon graft repair defect.
出处
《中国医药导报》
CAS
2007年第11X期76-77,共2页
China Medical Herald
关键词
同种异体
肌腱移植
深低温
生物力学
Allograft
Tendon transplantation
Deep hypothermia
Biomechanics
