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Moving forward in colorectal cancer research, what proteomics has to tell 被引量:3

Moving forward in colorectal cancer research, what proteomics has to tell
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摘要 Colorectal cancer is the third most common cancer and is highly fatal. During the last several years, research has been primarily based on the study of expression profiles using microarray technology. But now, investigators are putting into practice proteomic analyses of cancer tissues and cells to identify new diagnostic or therapeutic biomarkers for this cancer. Because the proteome reflects the state of a cell, tissue or organism more accurately, much is expected from proteomics to yield better tumor markers for disease diagnosis and therapy monitoring. This review summarizes the most relevant applications of proteomics the biomarker discovery for colorectal cancer. Colorectal cancer is the third most common cancer and is highly fatal. During the last several years, research has been primarily based on the study of expression profiles using microarray technology. But now, investigators are putting into practice proteomic analyses of cancer tissues and cells to identify new diagnostic or therapeutic biomarkers for this cancer. Because the proteome reflects the state of a cell, tissue or organism more accurately, much is expected from proteomics to yield better tumor markers for disease diagnosis and therapy monitoring. This review summarizes the most relevant applications of proteomics the biomarker discovery for colorectal cancer.
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2007年第44期5813-5821,共9页 世界胃肠病学杂志(英文版)
关键词 PROTEOMICS Colorectal cancer BIOMARKER 结肠癌 高致命性 癌细胞 治疗方法
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