摘要
如何提高脓毒症病人营养支持的效果是当前的热点和难点之一。本实验前瞻性地对比观察了不同蛋白质供应负荷 0 .2 5g N/ ( kg· d) vs0 .35g N/ ( kg· d) ,在脓毒症病人全胃肠外营养支持中对蛋白质代谢状况的影响。结果发现 ,与低氮量 TPN相比 ,高氮量 TPN支持可改善血浆蛋白水平 ,增加累积氮平衡 ,但尿中 3- MH排出量也有相应增加。结论 :脓毒症病人行高氮量 TPN支持 ,能进一步改善氮平衡 ,但有可能加重应激程度 。
It is still difficult to achieve optimal nutritional effect in the septic patient.The objectives of this prospective study are to determine the effect of increasing N intake on the metabolic response to TPN in the septic patient,containing either0 .2 5 g N/ (kg· d) or0 .35 g N/(kg· d) .On the high- but not the low- N intake there were further beneficial effects on net protein levels in blood and nitrogen balance.The results showed that TPN containing high N instake can further achieve nitrogen bal- ance in the septic patient,although it may stimulate the catabolism of protein and further evoke the stress to responses.
出处
《肠外与肠内营养》
CAS
1997年第3期135-137,共3页
Parenteral & Enteral Nutrition
关键词
脓毒症
全胃肠外营养
营养支持
蛋白
代谢
Sepsis Nitrogen bal- ance Total parenteral nutrition Pro- tein intake