摘要
蛋白转导域（protein transduction domain，PTD）是一种很有前景的蛋白转运工具，体内和体外实验显示其可以有效的将外源性蛋白转运入细胞内，已有多种方法用于改建PTD，证实PTD变体具有同样的蛋白转导特性。现就PTD的蛋白转运研究进展进行综述。
over the past several years, PTD is promising tools for transducing proteins and has been shown to be an effective way of delivering proteins into cell in vitro and in vivo.Various approaches have been applied for taming of the PTD. This has resulted in better PTD variants which are efficient in protein delivery. This paper reviews the development on PTD for protein transduction.
出处
《世界感染杂志》
2007年第5期359-361,382,共4页
World Journal of Infection
基金
国家自然科学基金项目（30571669/C030114）
关键词
蛋白转导域
蛋白转运
跨细胞转运
亲溶酶体剂
Protein transduction domain
protein delivery
transcellular Protein transduction domain
lysosomotropic agent
