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T淋巴细胞与炎症性肠病

T lymphocytes and inflammatory bowel diseases
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摘要 T淋巴细胞是具有特异性免疫功能的一种白细胞,它接受抗原刺激变成致敏细胞后乃分化繁殖成具有免疫活性的细胞,其免疫作用包括排斥移植来的异体组织、破坏肿瘤细胞、抑制病毒与细胞繁殖等。炎症性肠病(IBD)是一种病因尚不十分清楚的慢性非特异性肠道炎症性疾病,包括溃疡性结肠炎(UC)和克罗思病(CD)。炎症性肠病与自身免疫密切相关,T淋巴细胞在其发生发展中发挥重要的作用。 T lymphocytes, as one kind of white blood cells with specific immune function, develop into sensitized cells under antigenic stimulation, and differentiate into immunological competent cells. The allergized T lymphocytes are mainly involved in graft rejection, killing tumor cells, and inhibition of virus and bacteria replication, etc. The inflammatory bowel diseases, as one kind of cause-undetermined, chronic, and non-specific intestinal tract inflammatory diseases, include ulcerative colitis (UC) and Crohn's disease (CD). Inflammatory bowel diseases were closely related to autoimmunity and T lymphocytes play significant roles in their development.
作者 许昌泰
出处 《世界感染杂志》 2007年第5期355-358,370,共5页 World Journal of Infection
基金 陕西省卫生厅基金资助(201MD26)
关键词 炎症性肠病 溃疡性结肠炎 克罗恩病 T淋巴细胞 细胞因子 Inflammatory bowel diseases ulcerative colitis Crohn's disease T lymphocytes cytokine
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