摘要
目的探讨联合检测催乳激素(PRL)和抗心磷脂抗体(ACA)在子宫内膜异位症(EMS)诊断中的应用价值。方法将90例EMS患者按美国生育学会(AFS)修正的分期法分为轻度组(Ⅰ/Ⅱ期)41例和重度组(Ⅲ/Ⅳ期)49例,以10例正常生育年龄妇女做为对照组。采用时间分辨荧光免疫法检测血清PRL,ELISA法检测血清ACA。结果(1)EMS轻度组和重度组血清PRL水平及ACA阳性率分别为(642.60±419.69)u/ml、(647.97±289.76)u/ml和63.4%、71.4%,差异无统计学意义(P>0.05),但均明显高于健康对照组(P<0.05)。(2)轻度组血清ACA阳性率34.1%,显著高于重度组和对照组(P<0.05)。结论联合检测血清PRL和ACA,有助于EMS的诊断和分期。
Objective The study was to investigate the value of serum PRL and ACA detection in the diagnosis of endometrisis. Methods Serum PRL by time - resolved fluorescence assay and ACA by ELISA were detected in 41 EMS patients with stageⅠ/Ⅱ ,49 EMS patients with stage Ⅲ/Ⅳ and 10 normal women. Results （ 1 ） The positive rate and average concentrations of PRL in EMS patients with stage Ⅰ/Ⅱ and stage Ⅲ/Ⅳ were obviously higher compared with healthy control （ P 〈 0.05 ）. （ 2 ） The positive rate of ACA in EMS patients with stage Ⅰ/Ⅱ was 34.1% and was obviously higher compared with EMS patients with stage Ⅲ/Ⅳ and healthy control （P 〈 0. 05 ）. Conclusion Measurement of serum PRL and ACA may provide a valuable tool in the diagnosis and estimation of endometrisis.
出处
《中国临床保健杂志》
CAS
2007年第5期449-450,共2页
Chinese Journal of Clinical Healthcare
基金
国家自然科学基金(30471805)
