摘要
报告30例尸肾移植应用Swan－GanZ导管监测术中如心静脉压（CVP）、平均肺动脉压（PAP）、肺动脉舒张压（PDAP）、肺毛细血管楔压（PCWP），其中5例取心房血放免法测定心房利销多肽（ANP）。根据开放吻合血管时PDAP水平分为一组。结果PDAP＜2kPa组术后第2～3灭血肌酥水平明显高于PDAP≥2kPa组（P＜0．05），且2例发生急性肾小管坏死（ATN）需血透治疗。开放吻合血管时，ANP水平明显比术前高（P＜0．05），提示满意的心脏容量负荷可以促进肾移植早期功能恢复，降低术后ATN发生。ANP对术后肾功能早期恢复起一定作用。
Central venous pressure (CVP), mean pulmonary artery pressure (PAP), pulmonary diastolic arteries pressure (PDAP) and pulmonary capillary wedge pressure (PCWP) were monitored in 30 cases of cadaveric renal transplantation through the Swan Ganz catheter during operation, and ANP of artrial blood in 5 cases out of the 30 cases mcasured by radioimmunoassay.The patients were divided into two groups according to PDAP levels at the time of releasing the vascular clamps. The results showed that the levels of serum creatinine on 2nd to 3nd day postoperation in group 1 (n= 10) with PDAP<2 kPa were significantly higher than that in group 2 (n=20) with PDAP≥2 kPa (P<0. 05), and 2 cases having acute tubular necrosis (ATN) in group 1 needed dialysis treatment. The levels of ANP were significantly higher at the time of releasing the vascular clamps than those before operation. This study suggests that satisfactory cardiac volume load can promote early function recovery of transplanted kidney and decrease the occurrence of postoperative ATN. ANP had some roles for the recovery of early renal function.
出处
《中华器官移植杂志》
CAS
CSCD
1997年第2期108-110,共3页
Chinese Journal of Organ Transplantation
关键词
肾移植
心脏容量
急性
肾小管坏死
Renal/transplantation Cardiac volume Acute tubular necrosis
