摘要
目的：探讨青年乳腺癌的临床和病理特点，并对影响其预后的相关因素进行分析。方法：回顾性分析我院1989年12月～2000年12月收治的99例30岁及以下组乳腺癌患者的临床病理资料，观察患者长期生存率，分析临床病理特点及影响预后的因素。结果：本组99例病理类型中以浸润性癌占多数，高达98．99％；3年生存率为88．78％、5年生存率为68．37％，并随临床分期的增高而降低（P〈0．05）。肿瘤直径≤3cm和〉3cm的患者其5年生存率分别为75．56％、62．96％（P〈0．05）。腋窝淋巴结转移阴性患者与阳性患者5年生存率分别为75．61％、57．14％（P〈0．05）。结论：对于青年乳腺癌患者，肿瘤的临床分期和大小、腋窝淋巴结转移和综合治疗与否是影响预后的独立因素。因此，应尽可能做到早期诊断，早期进行正规的综合治疗，以提高患者的生存率。
Objective：To explore the clinical and pathologic characteristics of breast cancer in women less than 30 years of age and the influencing factors on survival . Methods：The clinical and pathologic features, long term survival ratios and prognostic factors of 99 breast cancer patients under 30 years, who were treated from December 1989 to December 2000, were retrospectively reviewed and analyzed by 10.0 statistic software, Results ： Invasive carcinoma was the main pathological type, which accounted for 98.99 %, Their 3- year and 5-year survival rates were 88, 78% and 68.37% respectively, which decreased along with their clinical stage increasing. For the patients with diameters of tumor ≤ 3 cm and 〉 3 cm, the 5-year survival rates were 75, 56% and 62, 96% respectively （ P 〈 0.05 ）. For the patients with negative and positive axillary lymph nodes metastasis, the 5-year survival rates were75.61% and 57. 14% respectively （ P 〈 0, 05 ）. Condusions： The clinical stage, tumor size, axillary lymph nodes metastasis and treatment modality are independent prognostic factors for breast cancer young patients. So being early diagnosed and treated by a combined therapy can greatly improve survival rates.
出处
《解剖与临床》
2007年第5期338-340,共3页
Anatomy and Clinics
关键词
乳腺癌
病理
预后
Breast cancer
Pathology
Prognosis
