摘要
【目的】比较三种不同药物肛门内置入后对取环手术镇痛及宫口松弛的作用。【方法】将90例择期行取环手术的妇女随机分为三组,分别于肛门内置入复方吲哚美辛栓1粒(A组),或0.4 mg米索前列醇(B组),或者安慰剂甲硝唑片200 mg(C组),1 h后行取环手术。术中判断宫颈软化程度及阴道出血量,记录手术时间和各种副反应以及最终能否取出宫内节育器,术毕患者评价术中疼痛视觉模拟评分(VAS)。【结果】三组一般资料差异无显著性,宫颈软化程度C组显著低于A、B两组,C组较其他两组手术时间显著为长、手术成功率显著为低,术中疼痛VAS评分A组<B组<C组。【结论】复方吲哚美辛栓在取环手术前直肠内应用,可在一定程度上软化宫颈、缩短手术时间、提高手术成功率,并且可以减轻术中疼痛。
[Objective] To compare the effect of three different intra-anal suppositoria on analgesia and cervical malacoma after extraction of intrauterine device （IUD）. [Methods] Ninety women elected for extraction of IUD were randomized into three groups, intraanally administered a pill of indomethacin and salbutamol sulfate suppository （Group A）, misoprostol 0.4mg （Group B） or flagyl tablet 200mg （Group C）, respectively. The operation was performed 1h later. The extent of cervical malacoma and amount of vaginal bleeding were determined. Time of each operation, side effects as well as rate of successful operation were recorded. Visual analogue score （VAS） of pain was evaluated for each patient. [Results]There was no difference among three groups in general data. The extent of cervical malacoma in Group C was obviously lower than that in Group A and Group B. Compared to Group A and Group B, Group C showed longer time of operation and lower success rate. The intraoperative VAS showed Group A〈Group B〈Group C. [Conclusion]When used intraanally and preoperatively, indomethacin and salbutamol sulfate suppository may promote cervical malacoma, shorten time of operation, increase success rate and alleviate intraoperative pain.
出处
《医学临床研究》
CAS
2007年第10期1703-1704,共2页
Journal of Clinical Research
