摘要
骨质疏松性骨折是骨质疏松症最严重的后果,骨质疏松性骨折的患病率与年龄、性别、种族等因素密切相关。骨质疏松性骨折的特点是:骨质量差,骨折愈合时间迟缓,再骨折的发生率较高。骨质疏松性骨折治疗包括骨折的外科治疗和抗骨质疏松症的治疗。抗骨质疏松的治疗,一方面可以提高骨量、改善骨质量,另一方面有降低再骨折风险的重要临床意义;骨折的外科治疗应以简便、安全、有效为原则。由于骨的质量差,骨折后内固定物及植入物固定的牢固程度差,易发生松动,因此需要寻找更接近骨刚度和骨弹性模量的内植物,研发能更快速、有效改善骨量与骨质量的制剂以改进骨质疏松性骨折的治疗。在骨质疏松性骨折的治疗过程中骨折的外科治疗和抗骨质疏松症的治疗应并重,才可以达到更理想的骨质疏松性骨折的治疗效果。
Bone fracture is the most serious outcome of osteoporosis,the morbidity has been linked to age, gender and races. The characteristics of osteoporotic fracture include reduced bone quality, a delay in bone fracture union process, and a high incidence of re-fracture. The therapy of osteoporotic fracture includes surgical management and osteoporosis treatment. Osteoporosis treatment can improve bone quantity and bone quality, decrease the rate of fracture. The rule of surgical management is simpleness, safety, and efficacy. Because of poor bone quality, internal fixation and implant are easy lossened. Ideas for future research, such as development of a new implant with risary. In order to get a good outcome of osteoporotic fracture treatment, both surgical management and osteoporosis treatment are important.
出处
《基础医学与临床》
CSCD
北大核心
2007年第10期1088-1092,共5页
Basic and Clinical Medicine
