摘要
细胞外信号调节激酶是丝裂原激活蛋白激酶家族的重要成员。近年来发现其与肝纤维化的关系密切,可从多方面影响肝纤维化的形成。通过干预细胞外信号调节激酶通路,研究肝纤维化的发病机制和药物治疗是有希望的途径。
The extracellular signal-regulated kinase（ERK） is an important member of mitogen-activated protein kinase （MAPK） family. The ERK signaling pathway is involved in liver fibrosis in many ways. It is a promising way to study the pathogenesis and therapy of liver fibrosis through intervention of ERK signaling pathway.
出处
《国际消化病杂志》
CAS
2007年第5期370-372,391,共4页
International Journal of Digestive Diseases
基金
福建省科技开发计划项目(No2005D094)
关键词
细胞外信号调节激酶
肝纤维化
肝星状细胞
Extracellular signal-regulated kinase
Liver fibrosis
Hepatic stellate cell
