摘要
目的探讨EVLT(静脉腔内激光治疗)术后残留症状的影响因素,建立Logistic回归模型,评价其预测术后残留症状的灵敏度、特异度和准确度。方法对163例(241条腿)下肢静脉曲张行EVLT术的患者年龄、性别、血小板、静脉炎史、家族遗传史、体重、凝血酶原时间、下肢股浅静脉内径、股总静脉内径、反流时间、反流平均速度、正常血流平均速度、反流指数等指标进行单因素分析,取其中有统计学意义的变量作多因素Logistic回归分析。结果患者的年龄、静脉炎史、家族遗传史、凝血酶原时间、下肢股浅静脉内径、股总静脉内径、反流指数等指标与术后残留症状密切相关。Logistic回归分析共有4个因素进入Logistic回归方程,作用的强弱依次是:家族遗传史、反流指数、下肢股浅静脉内径、凝血酶原时间。Logistic回归预测模型为:=1/[1+exp∑(4.150-2.7231-2.7842-0.0973+1.8134)],它判断下肢静脉曲张EVLT术后残留症状的准确度为81.39%,灵敏度为79.88%,特异度为80.93%。结论家族遗传史、反流指数、下肢股浅静脉内径、凝血酶原时间为下肢静脉曲张EVLT术后残留症状的主要危险因素,所建立的Logistic回归模型能较好地预测下肢静脉曲张EVLT术后残留症状的发生率。
Objective To investigate the risk factors of postoperative residual symptoms, and establish logistic regression model to evaluate the accuracy, sensitivity and specificity for predicting postoperative residual symptoms in patients with varicose veins of lower extremity by Endovenous Laser Treatment. Methods Casecontrol study was used to retrospectively investigate the clinical data of varicose veins of lower extremity cases. Firstly, single factor analysis was used in the age, gender, thrombocytopenia, phlebitis history, family history, weight, prothrombin time, lower extremity superficial femoral vein diameter, common femoral vein diameter, reflux time, reflux average velocity, normal blood flow velocity and reflux index.Then, multivariate Logistic analysis was used in the selected variables. Results Seven variables, including age, phlebitis history, family history, prothrombin time, lower extremity superficial femoral vein diameter, common femoral vein diameter and reflux index were selected through single factor analysis. By Logistic regression analysis, it was revealed that there were four significant factors for postoperative residual symptoms in diminishing sequence as family history, reflux in- dex, lower extremity superficial femoral vein diameter and prothrombin time. Logistic regression equation was as following： P= 1/[ 1 ＋exp ∑（4.150-2.723χ1-2.784χ2-0.097χ3＋ 1.813χ4）]. The accuracy, sensitivity and specificity of the Logistic model was 81.39%, 79.88%, 80.93%. Conclusion Family history, reflux index, lower extremity superficial femoral vein diameter and prothrombin time were the main risk factors of postoperative residual symptoms in patients with varicose veins of lower extremity by Endovenous Laser Treatment. The Logistic regressive model based on these factors is reliable in predicting the postoperative residual symptoms.
出处
《医学新知》
CAS
2007年第5期264-266,269,共4页
New Medicine
关键词
下肢静脉曲张
EVLT
术后残留症状
回归分析
varicose veins of lower extremity
Endovenous Laser Treatment
postoperative residual symptoms
regressive analysis
