摘要
用FT-IR、XRD、SEM和TGA等研究了4种不同模拟体系中胆红素钙晶体的成核与生长情况,考察了生物大分子和CO2对胆红素钙的成核与结晶等的影响。结果表明,水溶液中胆红素钙很难结晶形成晶体结构,但在暴露大气中的葡聚糖水溶液模拟体系中则形成了含质量分数为12%碳酸钙的胆红素钙/碳酸钙复合晶体。在此过程中,CO2气体促进了碳酸钙晶体的形成,碳酸钙晶体不同晶面的选择吸附性能和葡聚糖分子的含O功能团为胆红素钙的成核提供了有效位点和定向调控作用,共同模板作用诱导调控了在2θ为19.8°、21.8°有强衍射峰的胆红素钙晶体的形成。晶态胆红素钙具有明显的热分解温度,而处于非晶态时则无此种现象。
The nucleation and crystal growth of calcium bilirubinate crystalls in four different aqueous biomimetic systems were studied by FT-IR, XRD, SEM and TGA, and the effect of biomacromolecules and CO2 on the crystal nucleation of the calcium bilirubinate was investigated. The results indicated that the calcium bilirubinate crystals couldn＇t form spontaneously in the aqueous solution, while multiple crystals of calcium bilirubinate and calcium calcite coexisted and the mass content of the calcium calcite was about 12%. In the course of the nucleation and growth of the multiple crystals, crystal calcium bilirubinate with two obvious X-diffraction peaks at 2θ 19. 8° and 21.8° Were induced by the dextran and the calcite crystal formed under the effect of CO2 in the air. In the process, proper sites for the nucleation of calcium bilirubinate were provided by the crystal surface of the calcium calcite and the oxygenous function of the dextran molecules due to the effect on the coordination between the Ca^2＋ ions and the bilirubin, and the growth of the crystal calcium bilirubinate with a distinct decomposition temperature was induced.
出处
《应用化学》
CAS
CSCD
北大核心
2007年第10期1132-1135,共4页
Chinese Journal of Applied Chemistry
基金
国家自然科学基金资助项目(20371001
20471001
20501001)
安徽省高分子重点实验室项目
关键词
胆红素钙
生物模拟
成核与晶体生长
葡聚糖
碳酸钙
calcium bilirubinate, biomimetic, nucleation and crystal growth, dextran, calcium calcite
