摘要
目的 建立伤科七味片（马钱子粉、延胡索）的质量标准。方法 采用TLC法对延胡索干浸膏进行了鉴别试验;采用HPLC法测定马钱子粉的含量。以C18化学键合硅胶为固定相,以甲醇—离子对溶液为流动相。结果 在TLC色谱中检出延胡索。士的宁在10.21-102.1μg/mL范围内线性关系良好,平均回收率为99.1%,RSD为1.35%。结论 所建立的方法简便可行,重现性好,为伤科七味片质量控制提供了方法。
Objective To establish the quality standard for Shangkeqiwei Tablet（Semen strychni pulveratum, Rhizoma corydals）. Methods TLC was used for the qualitative identification of Rhizoma corydals. Semen strychni pulveratum puerarin was determined by RP-HPLC. The stationary phase consisted of C18 chemistry key agrees well with silica gel. The mobile phase consisted of methanol-ion pair solution. Results It was shown that a good linear relationship existed in the range of 10.21 - 102.1 mg/L of strychnine, the average recovery was 99.4 %, RSD was 1.25 %. Conclusion This method is simple, feasible and reproducible, it could be used for the quality control of Shangkeqiwei Tablets.
出处
《实用药物与临床》
CAS
2007年第5期311-313,共3页
Practical Pharmacy and Clinical Remedies
