摘要
目的:观察新伯氏液基薄层细胞学在筛查宫颈癌及癌前病变中的临床应用。方法:2404例妇女进行了液基薄层细胞学检查,细胞学评价方法采用TBS分级系统。结果:在2404例患者新伯氏液基薄层细胞学标本中,宫颈细胞学正常范围(不包括感染和炎症反应)仅49例(2.04%),轻度炎性病变404例(16.8%),中度炎性病变953例(39.6%),重度炎性病变735例(30.6%),细胞学阳性病例263例,阳性检出率为10.9%。其中鳞状上皮内低度病变72例(2.9%),鳞状上皮内高度病变38例(1.6%),宫颈癌9例(0.38%),意义不明的不典型鳞状细胞88例(3.7%),不排除上皮内度病变的不典型鳞状细胞13例(0.5%),人乳头瘤病毒感染12例(0.5%)。结论:新伯氏液基薄层细胞学是筛查宫颈癌及癌前病变的一种有效方法,育龄期妇女要定期进行妇科检查。
Objective To assess the application of thinPerp liquid-based cytology test for cervical disease screening.Methods The cervical specimen of 2404 patients were processed with thinPrep liquid-based cytology test and evaluated according to the Bethesda system.Results In the 2404 cases detected by thinPerp liquid-based cytology test,only 49 cases（2.04%）were normal,953 cases（39.6%）had moderate inflammation,and 735 cases（30.6%）had severe inflammation.The positive rate of thinPerp liquid-based cytology test was 10.9% of 263 positive cases.72 cases were diagnosed low grade squamous intraepithlial lesion（2.9%）,38 cases high grade squamous intraepithelial lesion（1.6%）,9 cases cervical cancer（0.38%）,88 cases atypical squamous cells of undermined signification（3.7%）,13 cases atypical squamons cells-high grade（0.5%）,and 12 cases（0.5%）human papillomaviral infection.Conclusion ThinPrep liquid-based cytology test is an effective method for cervical lesion screening.Child-bearing period women should receive a routine cervical cancer screening.
出处
《实用诊断与治疗杂志》
2007年第11期830-832,共3页
Journal of Practical Diagnosis and Therapy
关键词
液基薄层细胞学检测
TBS系统
宫颈病变
ThinPrep liquid-based cytology test
Bethesda system
cervical lesion
