摘要
目的研究肝撞击伤后气腹压力对肝动脉血流量的影响。方法通过建立肝撞击伤模型，按失血量以及气腹压力的不同，随机分为9组。采用彩色微球法检测气腹前、气腹30min、2h以及撤去气腹后30min肝动脉血流量的变化。结果10、15mmHg气腹下30min，12ml／kg失血组肝动脉血流量明显少于6ml／kg失血组（P〈0．05）。6ml／kg失血组，15mmHg气腹下30min，肝动脉血流量明显少于10mmHg气腹组（P〈0．05）；12ml／kg失血组，15mmHg气腹下30min，肝动脉血流量明显少于其余两种气腹压力组（P〈0．05）。结论肝撞击伤伴失血后肝动脉血流量的变化与失血量、气腹压力以及气腹持续时间等有密切联系。
Objective To investigate the hepatic arterial flow （HAF） under different intra-abdominal pressures in controlled hemorrhage rabbit models with liver injury. Methods Seventy-five New Zealand rabbits were divided into 9 groups according to the volume of blood loss and the intra-abdominal pressure. Color microspheres were used to measure the HAF before pneumoperitoneum, 30 minutes under pneumoperitoneum, 2 hours under pneumoperitoneum and 30 minutes after pneumoperitoneum. Results Under the intra-abdominal pressure of 10 and 15 mm Hg for 30 minutes, the HAF of the group which had a blood loss of 12 ml/kg was significantly smaller than that of the 6 ml/kg group （ P 〈0.05）. After losing blood of 6 ml/kg, the HAF of the group under the intra-abdominal pressure of 15 mm Hg for 30 minutes was significantly smaller than that of the 10 mm Hg group （ P 〈0.05）. After losing blood of 12 ml/kg, the HAF of the 15 mm Hg group for 30 minutes was significantly smaller than that of the 5 mm Hg group and 10 mm Hg group （ P 〈 0.05 ）. Conclusions The changes of the HAF after liver injury may be related to the volume of blood loss, the intra-abdominal pressure and the pneumoperitoneum duration.
出处
《中华消化外科杂志》
CAS
CSCD
2007年第5期360-362,共3页
Chinese Journal of Digestive Surgery
基金
全军“十一五”面上课题资助项目（06MA190）
关键词
肝脏损伤
腹腔镜
气腹
肝动脉血流量
Liver injury
Laparoscope
Pneumoperitoneum
Hepatic arterial flow
