摘要
目的系统评价、汇总MRI对前列腺癌局部分期的诊断价值,分析场强、扫描序列、成像线圈等技术参数对分期准确性的影响,分析论著发表时间、样本含量对研究结果的影响。资料与方法以“magnetic resonance imaging”、“prostatic neoplasms”、“staging”等为检索词在PubMed、MEDLINE中检索自1985年以来公开发表的关于人类前列腺癌MR分期的英文文献。对满足Meta分析要求的文献进行汇总,对场强、扫描序列、成像线圈等技术参数进行亚组分析,对文献发表时间、样本含量与分期准确性进行相关分析。结果直肠内线圈相对体线圈有较高的分期准确性,其汇总敏感性、特异性、汇总受试者工作特征曲线下面积（AUCSROC）分别为0.74（0.70-0.77）、0.74（0.69-0.78）、0.81（0.77-0.86）。快速成像序列相对普通成像序列有较高的分期准确性,其汇总敏感性、特异性、AUCSROC分别为0.78（0.75-0.80）、0.80（0.76-0.83）、0.83（0.79-0.86）。直肠内线圈联合快速成像序列对前列腺癌的局部分期准确性最高,其汇总敏感性、特异性、AUCSROC分别为0.82（0.79-0.85）、0.85（0.80-0.90）、0.91（0.87-0.95）。MR场强的高低对前列腺癌的分期准确性无影响。论著发表时间和分期准确性呈正相关,单篇论著的样本含量和分期准确性无明显相关性。结论快速成像序列、直肠内线圈会提高MRI对前列腺癌局部分期的准确性,两者联合应用对前列腺癌的分期准确性更高,随着时间的推移或阅片经验的积累,MRI对前列腺癌分期的准确性有所提高。
Objective To summarize and review the diagnostic value of magnetic resonance image （MRI） for local staging of prostate cancer,analyze the effect of technical parameters including field strength, scanning sequence, different coils on the accuracy of staging and analyze the effect of publication year of different study and sample size on study results. Materials and Methods PubMed and MEDLINE databases were searched for the published English articles since 1985 about human prostate cancer staging with MRI using ＂ magnetic resonance image＂, ＂ prostate cancer or neoplasm＂, ＂staging＂ as key word. Literature and related data which met the inclusion criteria were pooled, subgroup analysis about technical parameters including field strength, scanning sequence ,different coils and publication year of different study and sam- ple size was also made. Results Endorectal coil comparing with body coil had higher staging accuracy, the pooled sensi- tivity, specificity and AUC^SROC were 0.74 （0.70 -0.77）, 0.74 （0.69 -0.78 ） and 0.81 （0.77 -0.86）, respectively. The fast imaging sequence also had higher staging accuracy than conventional imaging sequence, the pooled sensitivity, specificity and AUC^SROC were 0.78（0.75 -0.80） ,0.80（0.76 -0.83 ） and 0.83（0.79 -0.86）, respectively. The staging accuracy of endoreetal coil combining fast imaging sequence was the highest, the pooled sensitivity, specificity and AUC^SROC were 0.82 （0.79 - 0.85 ）, 0.85 （0.80 - 0.90） and 0.91 （0.87 - 0.95 ）, respectively. Using high or low field strength had no influence on staging accuracy of prostate cancer. There was positive correlation between the staging accuracy and publication year of related articles. No obvious correlation between the accuracy of staging and sample size of any single article was found. Conclusion Fast imaging sequence and endoreetal coil can improve the local staging accuracy of prostate cancer. The combination of two techniques will lead to higher staging accuracy of prostate c
出处
《临床放射学杂志》
CSCD
北大核心
2007年第10期1009-1012,共4页
Journal of Clinical Radiology
关键词
磁共振成像
前列腺肿瘤
分期
META分析
Magnetic resonance image Prostate neoplasm Staging Meta analysis
