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职业性三氯乙烯药疹样皮炎合并感染危险因素的病例-对照研究 被引量:6

Case-control study on the risk factors of occupational trichloroethylene medicamentose-like dermatitis complicated with infection
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摘要 目的探讨职业性三氯乙烯(TCE)药疹样皮炎患者合并感染的危险因素,为控制其并发感染提供依据,并为该病患者防止感染采取有针对性的预防措施。方法选择我院2000年1月至2006年12月职业性TCE药疹样皮炎合并感染的住院病例,按1∶1配对进行病例-对照研究,采用回顾性调查方法,对暴露因素进行单因素及多因素条件Logistic回归分析。结果单因素条件Logistic回归分析筛选出9个危险因素与医院感染发生有关(OR=0.006~26.806,P<0.05),多因素条件Logistic回归分析筛选出发热情况、皮肤黏膜破损程度、病情是否危重与合并感染相关(OR=5.621~23.280,P<0.05)。结论皮肤黏膜破损、病情危重、合并感染前发热患者发生感染的危险性明显增大。 Objective To discuss the risk factors of occupational trichloroethylene medicamentose-like dermatitis complicated with infection, to provide basis for controlling hospital infection and to take targeted infection preventive measures for the patients with this disease. Methods The inpetients with occupational trichloreethylene medicamentose-like dermatitis complicated with infection from Jan 2000 to Dec 2006 in our hospital were chosen as the subjects. The case and the control were matched by 1:1 and a retrospective survey was applied. The exposure factors were analyzed by single variation and multivariate logistic regrossion analysis. Results With single variation logistic regression analysis, 9 factors were correlated with hospital infections ( OR = 0. 006 -26. 806, P 〈 0. 05 ). Multivariate logistic regression analysis showed that body temperature, damage degree of skin and mucous membrane, and the state of ill were correlative with the complicated infection ( OR = 5. 621 - 23.280, P 〈 0. 05). Conclusion Under the circumstances of skin and mucous membrane damage, dangerous ill status and fever, patients have obviously higher risk of infection incidence.
出处 《中国职业医学》 CAS 北大核心 2007年第5期383-385,共3页 China Occupational Medicine
关键词 职业性TCE致药疹样皮炎 感染 危险因素 病例-对照研究 Occupational trichlorccthylene medicamentose-like dermatitis Infection Risk factors Case-control study
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