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《血管紧张素转换酶抑制剂在心血管病中应用的中国专家共识》解读 被引量:3

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摘要 1977年施贵宝公司科学家Ondetti等根据血管紧张素转换酶(ACE)底物的化学结构推测设计出ACE的活性部位模型.1981年全球第一个血管紧张素转换酶抑制剂(ACEI)类药物卡托普利(开博通)上市并用于治疗高血压.被列入降压药物之一。20多年来对肾素一血管紧张素一醛固酮系统(RAAS)的认识不断深入及ACEI的临床应用日益扩展.目前ACEI已不仅是降压药物.还是心血管包括脑血管及肾血管疾病等靶器官的保护药物。
作者 徐成斌
出处 《临床药物治疗杂志》 2007年第5期1-5,共5页 Clinical Medication Journal
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