摘要
目的:建立气相色谱法同时测定麝香解痛膏中樟脑、冰片和桂皮醛的含量。方法:用蒸馏法制备供试品溶液,以聚乙二醇-20M 为固定相,涂布浓度为10%,玻璃柱,氮气为载气,FID 检测,检测口温度为250℃,柱温为程序升温。结果:在该色谱条件下,樟脑、冰片和桂皮醛三组分的分离度和线性关系良好,平均同收率(n=6)分别为99.7%(RSD=1.8%),99.2%(RSD=2.0%),98.6%(RSD=1.5%)。结论:本法简便、快速,准确性和再复性均好,可用于麝香解痛膏的质量控制方法。
Objective：To separate and determine camphor, synthetic borneol and cinnamaldehyde in Shexiang Jietong adhesive plasters. Methods：A GC method was developed. The sample solution was prepared by distillation with essential oil collector. The GC system consisted of glass column,with 10%PEG-20M as the stationary phase, nitrogen as the carrier gas, FID detector at 250 ℃ and programmed heating method. Results：The resolution and linearity of camphor, synthetic borneol and cinnamaldehyde were good with the recovery rate of camphor at 99.7% （ RSD = 1.8% ）, synthetic borneol 99.2% （ RSD = 2.0% ）, cinnamaldehyde 98.6% （ RSD = 1.5% ）, respectively. Conclusion：The method is convenient, rapid, accurate and reproducible, and can be used to control the quality of Shexiang Jietong adhesive plasters.
出处
《药物分析杂志》
CAS
CSCD
北大核心
2007年第9期1434-1436,共3页
Chinese Journal of Pharmaceutical Analysis
关键词
樟脑
冰片
桂皮醛
麝香解痛膏
气相色谱法
含量测定
camphor
synthetic borneol
cinnamaldehyde
Shexiang Jietong adhesive plasters
GC
assay
