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非肥胖的2型糖尿病肾病患者胰岛素敏感指数的变化

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摘要 目的:探讨非肥胖的2型糖尿病肾病患者胰岛素敏感指数的变化。方法:选择91例非肥胖的2型糖尿病患者,比较不同肾病患者之间的胰岛素敏感指数,同时检测、比较血清游离脂肪酸、肿瘤坏死因子-α水平的变化。结果:与正常蛋白尿患者相比,伴有微量白蛋白尿、大量蛋白尿、肾衰竭的2型糖尿病患者胰岛素敏感指数显著下降(P〈0.05~0.01),血清游离脂肪酸、肿瘤坏死因子-α水平显著增高(P〈0.05~0.01)。结论:糖尿病肾病患者胰岛素抵抗增加,可能与糖尿病肾病患者的血清游离脂肪酸、肿瘤坏死因子-α水平增高有关。
出处 《中国中西医结合肾病杂志》 2007年第9期539-540,共2页 Chinese Journal of Integrated Traditional and Western Nephrology
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参考文献12

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