摘要
目的 探讨铅对暴露人群骨密度的影响,为慢性铅中毒防治提供科学依据.方法 采用Lexxos型双能X线骨密度仪（DEXA,法国DMS公司生产）,测量接触铅工人（暴露组）301例（20～60岁）骨密度,另选择非接触铅工人173例（20～60岁）作为对照组.结果 铅暴露各组在髋部大转子以及前臂1/3处和前臂远端骨密度值均明显低于对照组（P＜0.05）;左髋部Ward＇＇s三角区男性40～49岁和50～59岁以及女性20～29岁和30～39岁4个年龄组中的骨密度值明显低于对照组（P＜0.05）;左髋部股骨颈男性30～39岁以及女性20～29岁和30～39岁年龄组中的骨密度值明显低于对照组（P＜0.05）.男性铅暴露组的骨质疏松发病率明显高于对照组（P＜0.05）,而女性铅暴露组与对照组比较差异无统计学意义（P＞0.05）.结论 低骨密度的发生与铅暴露可能有关.应加强铅危害的预防.
Objective A study on bone mineral density of people exposed to lead, providing scientific basis for chronic lead poisoning. Methods Use Lexxos dual power X-ray absorptiometry （DEXA, made by DMS Co. , France） to measure 301 workers （age 20 to 60） exposed to lead, while choose 173 workers（age 20 to 60） unexposed to lead as a comparing group. Results In the groups exposed to lead, the bone mineral density of innominate bone and one third part and the farest end of forearm is evidently lower than the comparing group（ P 〈 0.05 ） , In male groups （ age 40 to 49, age 50 to 59 ） and female groups （ age 20 to 29, age 30 to 39 ） , the bone mineral density of the ward＇s triangle part of left thighbone is evidently lower than the comparing group（ P 〈 0.05 ）, so as to the bone mineral density of bone in left hipbone part in male groups（age 30 to 39）, female group （age 20 to 29） and female group （age 30 to 39） . Incidence of Osteoporosis in male group exposed to lead is evidently higher than comparing group（ P 〈 0.05）, while there is no meaning in statistics between female group exposed to lead and comparing group（ P 〈 0.05）. Conclusions Low bone mineral density might have relation with lead exposure, measures should be taken to enhance the prevention against the lead harm.
出处
《中国骨质疏松杂志》
CAS
CSCD
2007年第1期39-41,共3页
Chinese Journal of Osteoporosis
基金
广东省医学科学技术研究基金资助项目(A2004698)
关键词
铅暴露
骨密度
骨质疏松症
Lead exposure
Bone mineral density
Osteoporosis
