摘要
细胞粘附分子（cellular adhesion molecules，CAMs）是位于细胞表面的糖蛋白。它通过介导细胞与细胞、细胞与外基质间的相互作用，参与多细胞生物的多种生理及病理过程。E-钙粘附素（E-cad）与细胞间粘附分子-1（ICAM-1）是两种重要的细胞粘附分子，与多种肿瘤的发生发展以及浸润转移关系十分密切，近年来正成为研究的重点和热点。现就E-cad、ICAM-1在泌尿生殖系统肿瘤中的研究现状特别是与肿瘤的侵袭、浸润与转移关系作一综述。
cellular adhesion molecules （CAMs） is a cell-membrance glucoprotein. It participates many physio and patho-processes of organisma multicellularis by conducting interaction of cells and cells, cells and ecsubstances. Epithelial cadherin（E-cad） and intercellular adhesion molecule-l（ICAM-1） are two important cellular adhesion molecules, impacted on many tumors＇ development, infiltration , metastasis. They are becoming investigative emphasis and hot spot. Now we reviewing the investigative SQ of E-cad and ICAM-1 in carcinoma of urogenital system, especially associating with invasion and metastasis of carcinoma.
出处
《国际医药卫生导报》
2007年第19期113-117,共5页
International Medicine and Health Guidance News
