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冠心病患者核素心肌灌注断层显像对PTCA术疗效评价

Study of myocardial perfusion imaging in evaluating the efficacy of PTCA/percutaneous intracoronary stent implantation in patients with coronary heart disease
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摘要 目的应用^99mTc-甲氧异晴(MIBI)心肌灌注断层显像判断经皮冠状动脉腔内成形术(PTCA)及支架置入术的疗效。方法54例冠心病患者在PTCA/支架术前、术后分别行运动+静息或静息+硝酸甘油介入心肌灌注断层显像检查。结果PTCA/支架置入术后,患者的缺血心肌节段及不可逆灌注缺损节段减少,即术前分别为2.64±0.43及3.64±0.47,术后分别为1.54±0.29及2.34±0.40。结论成功的PTCA/支架置入术治疗能明显改善冠心病心肌缺血。核素心肌灌注断层显像对PTCA术的疗效评价准确可靠,为一种有价值的无创性方法。 Objective To evaluate the therapeutic efficacy of percutaneous transluminal coronary angioplasty(PTCA) or percutaneous intracoronary stent implantation in patients with coronary heart disease using myocardial perfusion imaging. Methods Stress - test or rest - intravenous nitroglycerin infusion ^99mTc - methoxyisobutylisonitrile (MIBI) myocardial perfusion imaging were performed in a group of 54 patients with coronary heart disease before and after PTCA/percutaneous intracoronary stent implantation. Results The number of myocardial segment with reversible or irreversible perfusion defects in patients before treatment were compared with that after treatment(2.64 ±0.43 vs 1.54 ±0.29, 3.64 ±0.47 vs 2.34 ±0.40,respectively), significant difference was found in the two methods ( P 〈 0.05). Conclusion PTCA/percutaneous intracoronary stent implantation can improve myocardial ischemia obviously. Myocardial radionuclide perfusion imaging is a feasible atraumatic method approach to assess the therapeutic efficacy of PTCA/percutaneous intracoronary stent implantation.
作者 闫新慧
出处 《中原医刊》 2007年第18期4-5,共2页 Central Plains Medical Journal
关键词 冠心病 MIBI 心肌灌注显像 经皮冠状动脉腔内成形术 Coronary heart disease MIBI Myocardial perfusion tomography Percutaneous transhminal coronary angioplasty
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