期刊文献+

不同剂量阿司匹林和波立维对阿司匹林抵抗患者血小板聚集功能的影响及护理 被引量:2

下载PDF
导出
摘要 目的观察不同剂量阿司匹林和波立维对冠心病阿司匹林抵抗患者血小板聚集功能的影响,并提出相应护理对策。方法筛选出冠心病患者中发生阿斯匹林抵抗的患者48例入选本研究,随机分为3组,分别给予阿司匹林100、300 mg和阿司匹林100 mg+波立维75 mg,14 d后采用全血电阻法检测血小板聚集功能。结果阿司匹林100 mg和阿司匹林300 mg患者的血小板聚集功能比较差异均无统计学意义(P>0.05);加服波立维可使二磷酸腺苷诱导的血小板聚集功能显著抑制(P<0.01),但对花生四烯酸诱导的血小板聚集无明显影响。结论加大阿司匹林剂量或合用波立维不能明显改善冠心病患者的阿司匹林抵抗,对该类患者应加强临床观察和护理。
出处 《广东医学院学报》 2007年第4期511-512,共2页 Journal of Guangdong Medical College
  • 相关文献

参考文献4

二级参考文献27

  • 1Patrono C,Bachmann F,Baigent C,et al.European Society of Cardiology.Expert consensus document on the use of antiplatelet agents.The task force on the use of antiplatelet agents in patients with atherosclerotic cardiovascular disease of the European society of cardiology.Eur Heart J,2004,25:166-181. 被引量:1
  • 2Eagle KA,Guyton RA,Davidoff R,et al.American College of Cardiology.American Heart Association Task Force on Practice Guidelines.American Society for Thoracic Surgery and the Society of Thoracic Surgeons.ACC/AHA 2004 guideline update for coronary artery bypass graft surgery:summary article:a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1999 Guidelines for Coronary Artery Bypass Graft Surgery).Circulation,2004,110:1168-1176. 被引量:1
  • 3Stein PD,Alpert JS,Bussey HI,et al.Antithrombotic therapy in patients with mechanical and biological prosthetic heart valves.Chest,2001,119:2205-2275. 被引量:1
  • 4Chen ZM,Jiang LX,Chen YP,et al.COMMIT (ClOpidogrel and Metoprolol in Myocardial Infarction Trial) collaborative group.Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction:randomised placebo-controlled trial.Lancet,2005,366:1607-1621. 被引量:1
  • 5Patrono C,Coller B,FitzGerald GA,et al.Platelet-active drugs:the relationships among dose,effectiveness,and side effects:the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.Chest,2004,126(3 Suppl):234S-264S. 被引量:1
  • 6Pearson TA,Blair SN,Daniels SR,et al.AHA Guidelines for Primary Prevention of Cardiovascular Disease and Stroke:2002 Update:Consensus Panel Guide to Comprehensive Risk Reduction for Adult Patients Without Coronary or Other Atherosclerotic Vascular Diseases.American Heart Association Science Advisory and Coordinating Committee.Circulation,2002,106:388-391. 被引量:1
  • 7Ridker PM,Cook NR,Lee IM,et al.A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women.N Engl J Med,2005,352:1293-1304. 被引量:1
  • 8Antithrombotic Trialists' Collaboration.Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death,myocardial infarction,and stroke in high risk patients.BMJ,2002,324:71-86. 被引量:1
  • 9Yusuf S,Zhao F,Mehta SR,et al.Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation.N Engl J Med,2001,345:494-502. 被引量:1
  • 10Juul-Moller S,Edvardsson N,Jahnmatz B,et al.Double-blind trial of aspirin in primary prevention of myocardial infarction in patients with stable chronic angina pectoris.Lancet,1992,340:1421-1425. 被引量:1

共引文献194

同被引文献11

引证文献2

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部