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帕金森病的细胞凋亡 被引量:5

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摘要 目前已经确认了帕金森病(PD)的多种发病机制,然而多巴胺能神经元最终究竟是以一种什么样的形式走向死亡,是凋亡还是坏死?或者是二者并存?我们就这一问题作一阐述。
出处 《中华老年医学杂志》 CAS CSCD 北大核心 2007年第9期709-712,共4页 Chinese Journal of Geriatrics
基金 国家重点基础研究发展计划(973计划)(2006CB5007(06)):国家自然科学基金(30471918)
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  • 1Oleksandr E, Tak V. Apoptosis: key in neurodegenerative disorders. Curr Neurovas Res, 2004, 1:355-371. 被引量:1
  • 2Mogi M, Togari A, Kondo T, et al. Caspase activities and tumor necrosis factor receptor R1 (p55) level are elevated in the Substantia nigra from parkinsonian brain. J Neural Transm,2000, 107:335-341. 被引量:1
  • 3Jellinger KA. Cell death mechanisms in Parkinson' s disease. J Neural Transm, 2000, 107 : 1-29. 被引量:1
  • 4Cadet JL, Harrington B, Ordonez S, et al. Bcl-2 overexpression attenuates dopamine-induced apoptosis in an immortalized neural cell line by suppressing the production of reactive oxygen species. Synapse, 2000, 35:228-233. 被引量:1
  • 5Akiko Y, Yasuhiro Y, Kiyokazu O, et al. Involvement of endoplasmic reticulum stress on the cell death induced by 6-hydroxydopamine in human neuroblastoma SH-SY5Y cells. Neurochem Res, 2006, 31:657-664. 被引量:1
  • 6Yoshinaga N, Murayama T, Nomura Y, et al. Apoptosis induction by a dopaminergic neurotoxin, 1 methyl-4-phenylpyridiniunl ion ( MPP^+ ), and inhibition by epidermal growth factor in GH3 cells. Biochem Pharmacol,2000, 60:111-120. 被引量:1
  • 7Alves C, Julie D, Frederic B. 6 Hydroxydopamine but not 1-methyl 4-phenylpyridinium abolishes alphasynuclein anti-apoptotic phenotype by inhibiting its proteasomal degradation and by promoting its aggregation. J Biol Chem, 2006, 281:9824-9831. 被引量:1
  • 8Dauer W, Kholodilov N, Vila M, et al. Resistance of alpha-synuclein null mice to the parkinsonian neurotoxin MPTP. Proc Natl Acad Sci USA,2002, 99: 14 524-14 529. 被引量:1
  • 9Machida Y, Chiba T, Takayanagi A, et al. Common anti-apoptotic roles of parkin and alpha-synuclein in human dopaminergic cells. Biochem Biophys Res Commun, 2005, 332:233-240. 被引量:1
  • 10Jiang H, Ren Y, Zhao J, et al. Parkin protects human dopaminergic neuroblastoma cells against dopamineinduced apoptosis. Hum Mol Genet, 2004, 13: 1745-1754. 被引量:1

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