摘要
目的:分析年龄、性别、季节、喂养方式对婴幼儿骨源性碱性磷酸酶(BALP)活性的影响,从而对小儿佝偻病的预防提供参考。方法:采用全血干化学和免疫浓缩技术检测血液中BALP活性,并比较年龄、性别、季节、喂养方式对婴幼儿BALP活性的影响。结果:1 030例中BALP≤200U/L者324例,占31.4%;201～249 U/L者218例,占21.2%;BALP=250 U/L者376例,占36.5%;251～299 U/L者72例,占7.0%;≥300 U/L者40例,占3.9%。年龄越小,临界水平和阳性百分率越高。但阳性率随着年龄的增长具有明显的下降趋势。6月、1岁以及2岁的婴幼儿BALP值有显著性差异(2χ=66.43,P<0.01);母乳、人工、混合3种不同喂养方式BALP有显著性差异(χ2=22.74,P<0.01)。结论:年龄、喂养方式对婴幼儿BALP活性有影响,提示对小儿佝偻病的早期诊断、疗效观察及预防需采取相应的措施。
Objective： To provide references for precautions against newborn nutritive rickets by analysis of the influential factors include age, sex, feeding ways, which induced bone alkaline phosphatase of newborn. Methods： Detecting avidity of bone alkaline phosphatase in blood based on technology of chemistry with blood and immune condensation, and comparing the influential factors of age, sex, season and feeding ways inducing avidity of bone alkaline phosphatase. Result： There were total 1 030 cases, 324 of which（31.40%） with BALP≤200U/L; 218 of which （21.2%） with 200U/L 〈BALP≤249U/L; 376 of which （36.5%） with BALP=250U/L; 72 of which （7.0%） with 251U/L ≤BALP≤300U/L; 40 of which （3.9%） with BALP〉300 U/L. It also found that the younger age of infants, the higher level of critical value and higher coverage of positive results, however, the incidence of masculine descends obviously with infants＇ age increasing, There have been significant differ- ences on BALPs value of infants with 6--month, 12--month and 24--month of age. The different feeding ways, such as breast--feeding, artificial feeding and mixed way have shown the statistical difference （P〈0. 05）. Conclusion： The relative measures should be adopted for early diagnoses and treatments to newborn nutritive rickets on the basis of the diverse influential Of age, sex, feed ways inducing bone alkaline phosphatase of infants,
出处
《江苏预防医学》
CAS
2007年第3期13-15,共3页
Jiangsu Journal of Preventive Medicine
关键词
婴幼儿
骨源性碱性磷酸酶
佝偻病
infant
bone alkaline phosphatase
newborn nutritive rickets
