摘要
目的探讨上消化道出血(uGB)的病因分布、发病趋势及相关因素。方法回顾性分析我院1985年至2005年2335例UGB住院患者的临床资料。结果①主要病因依次为:十二指肠溃疡(DU)、胃溃疡(GU)、急性胃黏膜损伤(AGML)、复合溃疡(CU)、胃癌(GC)、食管胃底静脉曲张(EGV)。②各年份UGB病因构成不完全相同,AGML发病构成比呈上升趋势,慢性浅表性胃炎(CG)、GC呈下降趋势,有统计学意义。③男性患者明显多于女性,男女之比3.6:1。尤其是消化性溃疡(PU)男女差异有统计学意义(P<0.01)。④在各年龄段中,UGB以40～49岁占比例最大,UGB主要病因在不同年龄段分布不完全相同。⑤不同季节各主要病因检出率不完全相同。冬春两季PU的发病例数明显多于夏秋两季,其他主要病因在四季分布无统计学意义(P>0.05)。结论PU、AGML、Gc、EGV是UGB的主要病因,AGML发病构成比呈上升趋势。CG、GC呈下降趋势,UGB的病因分布与年代变化、性别、年龄、季节等因素相关。
Objective To investigate the etiology and the incidence tendency of upper gastrointestinal bleeding （UGB） . Methods A retrospective study was conducted to analyze the clinical data of 2335 patients with UGB between 1985 and 2005. Results The most common causes of UGB were duodenal ulcer（DU） , gastric ulcer （ GU ）, acute gastric mucosal lesion （ AGML）. complex ulcer （ CU ）. gastric cancer （ GC ）. esophageal gastric varices （EGV）. The causes of bleeding in different years were different. Specifically AGML had a increased constituent ratio , and CG （chronic gastritis ）. GC showed an proportionate decrease with time. Incidence of UGB in male patients is higher than female patients, with a ratio 3.6 ： 1. The etiologies of UGB in different age groups were different. UGB was more common in winter and spring than thant in summer and autumn. Conclusion The most common causes of UGB are peptic ulcer （PU）. AGML. GC. EGV. With time, An increased constituent ratio is shown in AGML, with a decrease ratio in CG.GC. Gender, age, weather are all correlative factors involved in the occurrence of UGB.
出处
《中国医药》
2007年第11期669-670,共2页
China Medicine
关键词
上消化道出血
病因
发病趋势
Upper gastrointestinal bleeding
Etiology
Tendency of incidence
