摘要
目的探讨BSAP、MUM1在经典型霍奇金淋巴瘤的表达情况。方法对81例经典型霍奇金淋巴瘤应用免疫组织化学Envision二步法进行BASP、MUM1、BCL-6、CD10、CD3、CD20、CD15、CD30的标记。结果CD3、BCL-6、CD10全部阴性,BASP、MUM1、CD20、CD15、CD30的阳性率分别为58.02%、100%、7.41%、59.26%、100%。结论经典型霍奇金淋巴瘤的H/RS细胞起源于生发中心后期分化的B细胞,它是一种活化的B细胞。
Objective To investigate the expressions of BSAP and MUM1 in classical Hodgkin＇s lymphoma （CHL）. Methods The expressious of BSAP. MUM1, CD3, CD20, CD15 and CD30 were assessed with two-step Envision method in 81 patients with CHL. Results In all cases, expressions of CD3, BCL-6 and CDIO were negative, whereas the positive rate of BSAP, MUM1, CD20, CDI5 and CD30 were 58.02%, 100%, 7.41%, 59.26% and 100^, respectively. Conclusion The H/RS cells of classical Hodgkin＇s lymphoma appear to be derived from a later stage of germinal center B cells, and therefore, are activated B cells.
出处
《中国药物与临床》
CAS
2007年第9期670-671,共2页
Chinese Remedies & Clinics
基金
山西省青年基金资助项目(20051051)
