摘要
将４８例消化性溃疡患者分复发和非复发两组，分别测定血清胃蛋白酶元，其结果表明，血清胃蛋白酶元作为消化性溃疡复发预测指标具有显著的统计学意义。其复发病机中医辨证为本虚标实，本虚以脾胃气虚为主，标实与瘀血、气滞、火热有关。气虚血瘀与血清胃蛋白酶元Ⅰ的含量变化呈正相关。以益气化瘀中成药对非复发组血清胃蛋白酶元高值者，进行中药抗复发预防治疗，不仅自他觉症状明显好转，血清胃蛋白酶元Ⅰ亦明显下降。推测益气化瘀中药抗溃疡复发机理与影响胃粘膜泌酸腺区的主细胞数量及分泌功能有关。
cases suffering from peptic ulcer weredivided into tow groups:relapse and nonrelapse.Pepsinogen was separately determined inserlolgy.Results show that pepsinogen of serology,as deptic ulcercalculative index,marked statistics significance.According to thesyndromic differentiation of TCM thought,the relapse mechanism issecondary deficiency and primary excess.The secondary deficiency ispleen Qi and stomach Qi deficiency.The secondary deficiency is pleen Qi and stomach Qi deficiency.The primary excess becomes involved isblood stasis,Qi depressioon,fire and heat.Qi deficiency and bloodstasis are in direct proportion to the pepsinoggen 1.The Chinese drugsof tonifying Qi and dissolving stasis prevented and treated thepatients suffering from deptic ulcer,who hadn’t had a relapse.Thepatients’ symptoms were fangible on the mend.The pepsinogen I was tangibly reduced.It is cangible on the mend.The pepsinogen I was tangibly reduuced.It is calculated that the anti ulcerative relapsemechanism of the Chinese drugs of tonifying Qi and dissolving stasis isassociated with the number of major cells of gastric mucosa oxynticadenocar and the function of secrete.
出处
《中国中医基础医学杂志》
CAS
CSCD
1997年第2期38-40,共3页
JOURNAL OF BASIC CHINESE MEDICINE
基金
江苏省教委自然科学基金
关键词
消化性溃疡
胃蛋白酶元
中药
药理学
Deptic ulcer/Prevend and controla relapse/pepsinogen[W
