摘要
【目的】观察马齿苋合剂水提取液治疗生殖器疱疹的临床疗效。【方法】采用单纯随机抽样法将120例患者分为实验组、对照组各60例。实验组采用马齿苋合剂水提取液治疗,对照组采用抗病毒药物无环鸟苷治疗。两组均以7 d为1个疗程,连续治疗4个疗程后对两组临床疗效进行评定。【结果】实验组治愈33例,显效13例,好转11例,无效3例,总有效率为95.00%;对照组治愈19例,显效14例,好转18例,无效9例,总有效率为85.00%;两组比较,实验组临床总疗效优于对照组(P<0.05)。随访1年,实验组的年复发次数少于对照组(P<0.05),说明实验组的远期疗效优于对照组。毒副作用观察结果显示,实验组未出现不良反应,对照组少数病例出现药疹、出汗、恶心、头痛等症状。【结论】马齿苋合剂水提取液对生殖器疱疹有较好的治疗作用。
[ Objective ] To observe the therapeutic effect of water-extract of Herba Portulacae Mixture （HPM） for genital herpes. [ Methods ] One hundred and twenty patients with genital herpes were equally randomized into groups A and B. Group A received water-extract of MSP, and group B received acyclovir. Seven days constituted one treatment course. The therapeutic effect was evaluated after 4 continuous treatment courses. [ Results ] In group A, 33 were cured, 13 markedly effective, 11 effective, 3 ineffective and the total effective rate was 95.00% ; in group B, 19 were cured, 14 markedly effective, 18 effective, 9 ineffective and the total effective rate was 85.00%. The total effective rate in group A was better than that in group B （ P 〈 0. 05 ）. The result of oneyear follow-up showed that annual incidence was lower in group A than that in group B （ P 〈 0.05 ）, indicating that the long-term therapeutic effect is better in group A. No adverse reaction was found in group A. However, drug eruption, sweating, nausea and headache were found in some patients of group B. [ Conclusion ] HPM exerts a better therapeutic effect for genital herpes.
出处
《广州中医药大学学报》
CAS
2007年第5期368-370,共3页
Journal of Guangzhou University of Traditional Chinese Medicine
基金
江西省抚州市科技局资助课题(编号:2006016)
