摘要
目的了解中国不同地区医生胃食管反流病(GERD)的发病和诊治情况。方法中国医师协会消化医师分会采用随机抽样问卷方式,于2006年2月—6月在全国不同地区医院中对患有GERD的医生的发病和诊治情况进行调查。结果1010例患有GERD的医生接受调查,男性567例、女性419例,男女性别比为1.35:1,平均年龄为(41.1±10.3)岁,其中患病年龄以30～40岁最为多见。在胃食管反流症状中烧心502例(49.7%),胸骨后痛325例(32.2%),嗳气319例(31.6%),上腹痛313例(31.1%),咽部吞咽异物感88例(8.7%)。在被调查对象中467例(46.2%)曾行胃镜检查,食管黏膜正常者339例,占76.0%;反流性食管炎102例,占21.8%;Barrett食管10例,占2.2%。89.3%的被调查者曾服用质子泵抑制剂(PPI)治疗,平均起效时间为(13.2±36.5)h,服用药物的满意度为91.0%。相关分析显示年龄及性别与胃镜检查结果无相关性,临床症状及其严重程度与胃镜检查结果亦无相关性。回归分析显示症状缓解时间(P=0.0065)及服药方式(P=0.0003)与服用药物满意度存在负相关。结论患有GERD的中国医生临床症状主要表现为烧心、胸骨后痛、嗳气和上腹痛,胃镜检查是诊断反流性食管炎的重要依据,多数被调查者胃镜下表现为食管黏膜正常,选择服用PPI治疗疗效的满意度高。
Objective To explore the prevalence, diagnosis and management of GERD in doctors of China. Methods From February 2006 to June 2006, the prevalence, diagrosis and management of doctors with GERD in China were investigated using questionnaire by Chinese Association of Gastroenterologist and Hepatologist. Results One thousand and ten doctors with GERD were studied, including 567 male and 419 female, ratio of male to female was 1.35 ： 1, mean age was（41.1 ± 10.3） years old, most of them were among 30 to 40 years old. Heartburn was the predominant symptom, accounting for 49.7% of GERD subjects, the other main symptoms were chest pain（32.2%）, belching（31.6%）, epigastric pain（31.1%）. Most of the GERD patients（43. 9%） showed no mucosa lesions in endoscopy, erosive esophagitis and Barrett＇s esophagus covered 21.8% and 2.2% respectively. Nearly 89.3% of the surveyed doctors took proton pump inhibitors（PPI） as their first choice, mean time of effect was（13.2±36.5） hours. Ninty-one percent of GERD subjects were satisfied with the effect of PPI treatment. The analysis showed no correlation between gender and age with endoscopic diagnosis, main symptoms and severity of the disease. Logistic regression showed symptom relief time and method of medication had negative correlation with satisfaction with medicine. Conclusions Heartburn, chest pain, belching and epigastric pain were the most common symptoms in doctors with GERD in China. Endoscopy was important in diagnosis of erosive esophagitis, while most of the patients showed no lesions in endoscopy. PPI is their first choice with satisfaction.
出处
《中华消化杂志》
CAS
CSCD
北大核心
2007年第8期542-544,共3页
Chinese Journal of Digestion
关键词
胃食管反流病
观察
治疗
Gastroesophageal reflux diseases
Observation
Therapy
