摘要
目的评价氧驱博利康尼联合爱全乐雾化治疗对重症哮喘的疗效。方法重度持续哮喘患者40例随机分为两组,治疗组20例氧驱雾化吸入博利康尼联合爱全乐+基础治疗,对照组仅予以基础治疗。观察两组的疗效及激素用量、应用天数。结果气急缓解时间:治疗组(2.45±1.20)d,对照组(3.96±1.24)d(P<0.01);哮鸣音消失时间:治疗组(3.26±1.40)d,对照组(4.78±1.52)d(P<0.01);总甲强龙平均用量:治疗组(135±87.7)mg,对照组(253.5±87.65)mg(P<0.05);甲强龙应用天数:治疗组(3.05±2.06)d,对照组(5.9±2.87)d(P<0.01),两组比较有显著性差异。结论氧驱博利康尼联合爱全乐雾化对重症哮喘的治疗起效快,疗效好,激素应用时间缩短用量减少。
To assess the efficacy of oxygen impulsing terbutaline combined with ipratropium bromide in treating the acute attacks of asthma. Methods Fourty patients with severe asthma were randomly divided into the treatment group (20 cases) and control group (20 cases). Oxygen impulsing aerosol inhalation of terbutaline combined with ipratropium bromide and basic treatment was administered to those in the treatment group, whereas the control group only received basic treatment. The effects, dose of methylprednisolone and days of methylprednisolone were observed in the two group. Results. The average time for relief of short of breath was 2. 45 ± 1.20 in the treatment group and 3.96 ± 1.24 day in the control group (P 〈0.01 ). The time for disappearance of wheeziness was 3.26 ± 1.40 in the treatment group and 4.78 ± 1.52 day in the control group (P 〈 0. 01 ). The days of using the medication was 3.05 ± 2.06 in the treatment group and 5.9 ±2.87 in the control group (P 〈0. 01 ). Overall, the treatment group had much better clinical effects than that in the control group. Conclusion: Oxygen impulsing terbutaline combined with ipratropium bromide has a better onset timing, clinical effect and shorter period of using medication in treating exacerbations asthma.
出处
《临床肺科杂志》
2007年第10期1075-1076,共2页
Journal of Clinical Pulmonary Medicine
关键词
博利康尼
爱全乐
甲强龙
雾吸
重症哮喘
terbutaline
ipratropium bromide
methylprednisolone
aerosol inhalation
severe asthma