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植物磷酸化蛋白质组学的研究进展 被引量:5

Research Progress on Plant Phosphoproteomics
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摘要 蛋白质的磷酸化是一种最重要的蛋白质翻译后修饰方式之一。蛋白质的磷酸化和去磷酸化在生命过程中起着关键的调节作用。当前,磷酸化蛋白质组学的主要研究内容包括鉴定磷酸化蛋白、定位磷酸化位点、定量磷酸化水平,进而揭示磷酸化和去磷酸化在生命过程中所起的生物学功能。在介绍植物磷酸化蛋白组学的研究方法及目前进展的基础上,展望了植物磷酸化蛋白组学的研究前景。 Protein phosphorylation is the most important mode of post-translational modifications. Protein phosphorylation and dephosphorylation play a critical regulation function in the whole process of vital movement. The major objectives of the present phosphoproteomics include the isolation of global phosphorylation protein in the cell, the generation of global phosphorylation protein map, and the identification of phosphorylated site on phosphorylation protein, and then regulation functional analysis of phosphorylation and dephosphorylation in the life process. On the basis of introducing the research approaches and the latest progress on plant phosphoproteomics, this paper also looks into the prospects of phosphoproteomics.
出处 《中国农业科技导报》 CAS CSCD 2007年第4期43-48,共6页 Journal of Agricultural Science and Technology
基金 国家重点基础研究发展计划(2004CB117303 2006CB101706) 高等学校博士学科点专项科研基金(2005000306)资助
关键词 植物 磷酸化 磷酸化蛋白质组 质谱 分离与鉴定 plant phosphorylation phosphoproteome mass spectrometry isolation and identification
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参考文献29

  • 1Kersten B,Agrawal G K,Iwahashi H,et al..Plant phosphoproteomics:a long road ahead[J].Proteomics,2006,6:5517-5528. 被引量:1
  • 2Krupa A,Preethi G,Srinivasan N.Structural modes of stabilization of permissive phosphorylation sites in protein kinases:distinct strategies in Ser/Thr and Tyr kinases[J].J Mol Biol,2004,339:1025-1039. 被引量:1
  • 3Zolnierowicz S,Bollen M.Protein phosphorylation and protein phosphatases[J].EMBO J.,2000,19:483-488. 被引量:1
  • 4Venter J C,Adams M D,Myers E W,et al..The sequence of the human genome[J].Science,2001,91:1304-1351. 被引量:1
  • 5Kerk D,Bulgrien J,Smith D W,et al..The complement of protein phosphatase catalytic subunits encoded in the genome of Arabidopsis[J].Plant Physiol.,2002,129:908-925. 被引量:1
  • 6Hunter T.The phosphorylation of proteins on tyrosine:its role in cell growth and disease[J].Philos.Trans.R.Soc.,1998,353:583-605. 被引量:1
  • 7Agrawal G K,Thelen J J.Large scale identification and quantitative profiling of phosphoproteins expressed during seed filling in oilseed rape[J].Mol.Cel.Proteomics.,2006,5:2044-2059. 被引量:1
  • 8Scott C P.Phosphoproteomics in Arabidopsis:moving from empirical to predictive science[J].J.Exp.Bot.,2006,57:1523-1527. 被引量:1
  • 9Benschop J J,Mohammed S,O'Flaherty M,et al..Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis[J].Mol.Cel.Proteomics,2007,6:1198-1214. 被引量:1
  • 10Thomas P C,Timothy D.An enriched look at tyrosine phosphorylation[J].Nature Biotechnol.,2005,23:36-37. 被引量:1

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