摘要
目的探讨支气管激发试验在不典型哮喘中的诊断价值及意义。方法对147例不典型哮喘患者用肺功能仪测定基础肺功能及吸入不同剂量组胺后的肺功能,同时对PEF、FEV1、MMEF同步进行测定,观察三者的变化。结果147例患者支气管激发试验阳性62例(42.2%),可疑阳性31例(21.1%),正常54例(36.7%)。所有患者均顺利完成检查。阳性组结果提示MMEF下降与FEV1下降呈明显相关性,且MMEF下降的幅度大于FEV1的改变;可疑阳性组MMEF与FEV1亦呈同步下降,下降值均≥20%,幅度也大于FEV1;正常组MMEF与FEV1也有很好的同步性,且MMEF激发前后所测值(-x±s)P<0.05具有统计学意义。结论对临床高度怀疑哮喘而基础肺功能正常的病人,首选支气管激发试验以便作出早期诊断。
Objective To explore the diagnostic value of bronchial provocation test in asthmatic patients with atypical symptoms. Methods Basic lung function and lung function after inhaling different doses of histamine were tested by using pulmonary function test apparatus in 147 asthmatic patients with atypical symptoms. The change of FEV1, PEF and MMEF were observed before and after the test. Results In 147 patients ,62 cases（42. 2%） were positive,54 cases（36. 7%） were negative,and 31 cases （21. 1%）were suspiciously positive for the bronchial provocation test. All the patients undertook the test smoothly. The descent of FEV1 and MMEF was significantly correlated in positive patients, while the descent degree of MMEF is more than the change of FEV1. The suspiciously positive patients＇MMEF decreased more than 20% and related to FEV1. The change of MMEF was related to FEV1 in the negative patients and there was significant difference in MMEF before and after the test（P 〈0.05）. Conclusion the bronchial provocation test should be the first choice in diagnosing the patients highly suspicious of asthma with good base lung function.
出处
《贵州医药》
CAS
2007年第8期690-691,共2页
Guizhou Medical Journal
关键词
支气管激发试验
不典型哮喘
肺功能
Bronchial provocation test Atypical asthma Pulmonary function
