摘要
[目的]观察在硬膜外麻醉和全麻下腹腔镜胆囊切除术中血浆肾上腺素(E)、去甲肾上腺素(NE)HR、BP的变化。[方法]将40例拟行腹腔镜胆囊切除术患者随机分成全麻(GA)组和硬膜外(EA)组,每组20例,监测麻醉前,气腹前10 min、气腹后及放气后5 min各时点血浆NE、E浓度。[结果]EA组术中各时点NE浓度无明显变化,气腹前及气腹后E明显增高(P﹤0.05),术毕基本恢复(P﹥0.05);GA组气腹后NE和E均明显增高(P﹤0.05),术毕E仍未恢复(P﹥0.05)。[结论]两种麻醉方法术中均存在明显心血管应激反应,硬膜外麻醉下施行腹腔镜胆囊切除术中心血管应激反应较全麻轻。
[Objective] To observe the effects of epidural anesthesia （EA） and general anesthesia （GA） on the changes of plasma epinephrine （E） and norepinephrine （NE） during LC. [Methods] 40 patients undergoing LC were randomly and equally divided into GA group and EA group. The concentrations of plasma NE and E were measured at the following phases： before anesthesia, 10 minutes before introducing pneumoperitoneum, post-pneumoperitoneum and 5 minutes after operation. [Results] In EA group, the concentrations of NE were stabile at each phase, the concentrations of E significantly increased pre-and post-pneumoperitoneum （P〈 0.05） and returned to the base lime at the end of operation （P〉 0.05） ; In GA group, the concentrations of NE and E increased significantly after pneumoperitoneum （P 〈 0.05） and could not return to the base line at the end of operation （P 〉 0.05）. [Conclusions] Both general anesthesia and epidural anesthesia have obvious stress reaction, but the stress reaction inEA Group during LC is weaker than that in GA group.
出处
《现代预防医学》
CAS
北大核心
2007年第17期3391-3392,共2页
Modern Preventive Medicine
关键词
全身麻醉
硬膜外麻醉
腹腔镜胆囊切除术
心血管应激反应
General anesthesia
Epidural anesthesia
Laparoscopic cholecystectomy
Cardiovascular stress reaction
