摘要
目的了解机化性肺炎(organizing pneumonia,OP)的临床特点、类型、治疗及疗效,初步探讨隐原性机化性肺炎(COP)与继发性OP在临床表现、预后等方面的异同。方法回顾性分析自2002年7月至2007年4月我院17例OP患者的临床资料。结果15例为隐原性机化性肺炎,2例为继发于多发性肌炎的机化性肺炎。临床主要表现为咳嗽、进行性活动后呼吸困难,可有发热、盗汗等,肺部闻及爆裂音;影像学表现为双肺多发斑片状肺泡浸润影或线状、网格状影或结节状阴影,肺功能呈限制性通气功能减退,弥散功能降低。肾上腺皮质激素对隐原性机化性肺炎的疗效显著,而对继发于多发性肌炎的机化性肺炎的疗效欠佳。结论机化性肺炎是一临床病理综合征,易误诊为肺部感染、肿瘤等。隐原性机化性肺炎对肾上腺皮质激素有良好的效果,而继发于多发性肌炎的机化性肺炎临床表现重且预后差。
Objective To investigate the clinical features, types ,treatment and prognosis of organizing pneumonia（OP） and the difference between cryptogenic organizing pneumonia（COP） and polymyositis with OP. Methods A retrospective study of 17 patients with OP from July, 2002 to April,2007 was conducted. Results 15 patients had COP and 2 had polymyositis with OP. Their symptoms and signs were dyspnoea, cough, fever and crackles. Their chest radiograph showed bilateral patchy （alveolar） infiltrates or bilateral linear opacities. Their pulmonary function tests showed that decreased vital capacities and diffusing capacities. The patients with COP had a favourable outcome after treatment with corticosteroids, while the response of the patients with polymyositis with OP to corticosteroids was poor. Conclusions Organizing pneumonia is an inflammatory lung disease and a clinicopathological syndrome. Resolution of symptoms was more frequent after treatment with corticosteroids in patients with COP than those with polymyositis with OP.
出处
《老年医学与保健》
CAS
2007年第4期216-218,共3页
Geriatrics & Health Care
关键词
机化性肺炎
隐原性机化性肺炎
多发性肌炎
Organizing pneumonia
Cryptogenic organizing pneumonia
Polymyositis
