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糖代谢紊乱与鼻咽癌放射性皮炎关系的临床观察 被引量:10

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摘要 目的观察糖代谢紊乱对鼻咽癌放射性皮炎的影响。方法前瞻性观察住院鼻咽癌742例,治疗前后分别检测空腹和餐后2h血糖,分析血糖与放射性皮炎程度的关系。结果7例因放疗诱发了糖尿病,放疗中4例糖尿病发生了酮症酸中毒;放疗后糖代谢紊乱发生率高于放疗前(P<0.05);合并糖代谢紊乱者和单纯鼻咽癌患者3级以上放射性皮炎发生率分别为25.49%和9.38%,两组差异有统计学意义(χ2=16.027,P=0.000);FPG(r=0.099,P=0.007)、2hBG(r=0.088,P=0.016)与放射性皮炎程度均呈正相关。结论鼻咽癌患者放疗可诱发糖代谢紊乱,甚至诱发糖尿病;高血糖可加重放射性皮炎而影响鼻咽癌患者预后,应加强放射野皮肤的保护,并良好控制血糖。
出处 《广西医学》 CAS 2007年第8期1175-1176,共2页 Guangxi Medical Journal
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